$Unique_ID{BRK01336}
$Pretitle{Blood and Blood Forming Organs}
$Title{What Are Anti-Kell Antibodies?}
$Subject{anti-Kell antibodies}
$Volume{D-7}
$Log{}

Copyright (c) 1991   Tribune Media Services, Inc.


What Are Anti-Kell Antibodies?


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QUESTION:  I have been a regular blood donor since 1960.  Recently I received
a letter from our local Red Cross Blood Bank informing me that I have
anti-Kell antibodies and that doctors should be made aware of this if I ever
need a blood transfusion.  Exactly what are anti-Kell antibodies?

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ANSWER:  There are many types of antigens present on red cells.  An antigen is
any substance capable, under appropriate conditions, of producing an a
specific immune response.  Usually blood is typed for A, B, O and Rh-D
antigens during a normal test, but the other antigens, including Kell, Duffy,
Kidd (all named for their discoverers) and other Rh antigens may also produce
an antibody response.  When blood containing these antibodies comes in contact
with blood possessing the matching antigens, a reaction called "hemolysis"
(destruction of red blood cells) may occur.  No treatment is necessary, but
when continued transfusions are necessary, only blood that lacks the offending
antigens should be used.  Specifically for you, you would need blood that has
no Kell antigens, since your own blood now has anti-Kell antibodies.  It is
nothing you should be concerned about now, but is important information for
your physician should you require a transfusion.

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The material contained here is "FOR INFORMATION ONLY" and should not replace 
the counsel and advice of your personal physician.  Promptly consulting your 
doctor is the best path to a quick and successful resolution of any medical 
problem.
