$Unique_ID{BRK02168}
$Pretitle{}
$Title{TRIAMCINOLONE, NEOMYCIN, NYSTATIN, AND GRAMICIDIN COMBINATION (TOPICAL)}
$Subject{Myco Triacet (various manufacturers)
triamcinolone, neomycin, gramicidin, and nystatin (various manufacturers)
Tri-Statin (Rugby)}
$Volume{}
$Log{}

Copyright (C) 1991 Publications International, Ltd.


TRIAMCINOLONE, NEOMYCIN, NYSTATIN, AND GRAMICIDIN COMBINATION (TOPICAL)
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BRAND NAMES (Manufacturers):
     Myco Triacet (various manufacturers)
     triamcinolone, neomycin, gramicidin, and nystatin (various manufacturers)
     Tri-Statin (Rugby)
TYPE OF DRUG:
     Adrenocorticosteroid and anti-infective
INGREDIENT:
     Striamcinolone, neomycin, nystatin, and gramicidin
DOSAGE FORMS:
     Cream (0.1% triamcinolone; 2.5 mg neomycin; 100,000 units nystatin; and
       0.25 mg gramicidin per gram)
     Ointment (0.1% triamcinolone; 2.5 mg neomycin; 100,000 units nystatin;
       and 0.25 mg gramicidin per gram)
STORAGE:
     The cream and ointment should be stored at room temperature (never
       frozen) in tightly closed containers.  Discard any outdated medicine or
       medicine no longer needed.

USES

     Your adrenal glands naturally produce certain cortisone-like chemicals.
These chemicals are involved in various processes in the body (such as
maintenance of fluid balance, regulation of temperature, and reaction to
inflammation).  Triamcinolone belongs to a group of drugs known as
adrenocorticosteroids (or cortisone-like medications).  It is used to relieve
the skin inflammation (redness, swelling, itching, and discomfort) associated
with conditions such as dermatitis, eczema, and poison ivy.  How this drug
acts to relieve these disorders is not completely understood.  Neomycin and
gramicidin are antibiotics, which act to prevent the growth and multiplication
of infecting bacteria.  Nystatin is an anti-infective agent that is active
against the fungus Candida albicans.

TREATMENT

     Before applying this medication, wash your hands.  Then, unless your
doctor gives you different instructions, gently wash the area of skin where
the medication is to be applied.  With a clean towel, pat the area almost dry;
it should be slightly damp when you put the medication on.
     Apply a small amount of this medication to the affected area in a thin
layer.  Do not bandage the area unless your doctor tells you to do so.  If you
are to apply an occlusive dressing (like kitchen plastic wrap), be sure you
understand the instructions.  Wash your hands again after application.
     If you miss a dose of this medication, apply the dose as soon as
possible, unless it is almost time for the next application.  In that case, do
not apply the missed dose at all; just return to your regular dosing schedule.
Do not put twice as much of the medication on your skin at the next
application.
     Use this medication for the full length of time prescribed by your
doctor; do not take the medication for longer than the prescribed period.

SIDE EFFECTS

     Minor.

     Acne, burning sensation, irritation of the affected area, or skin
dryness.
     If the affected area is extremely dry or scaling, the skin may be
moistened by soaking in water or by applying water with a clean cloth before
applying the medication.  The ointment form is probably better for dry skin.
     A mild, temporary stinging sensation may occur after this medication is
applied.  If this persists, contact your doctor.

     Major.

     Tell your doctor about any side effects that are persistent or
particularly bothersome.  IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about
blistering, increased hair growth, itching, loss of skin color, rash,
secondary infection in the area being treated, or thinning of the skin with
easy bruising.  Also, if your symptoms of infection seem to be getting worse
rather than improving, you should contact your doctor.

INTERACTIONS

     This medication should not interact with other medications, as long as it
is used according to directions.

WARNINGS

     * Tell your doctor about unusual or allergic reactions you have had to
any medications, especially to triamcinolone or other adrenocorticosteroids
(such as amcinonide, betamethasone, clocortolone, cortisone, desonide,
desoximetasone, dexamethasone, diflorasone, flumethasone, fluocinolone,
fluocinonide, fluorometholone, flurandrenolide, halcinonide, hydrocortisone,
methylprednisolone, prednisolone, and prednisone) or to neomycin, nystatin, or
gramicidin.
     * Tell your doctor if you now have or if you have ever had circulation
problems, chicken pox, diabetes mellitus, peptic ulcers, shingles,
tuberculosis of the lungs or skin, vaccinia, or viral or fungal infections of
the skin in addition to a Candida infection.
     * If irritation develops while you are using this drug, immediately
discontinue its use and notify your doctor.
     * Do not use in the eyes; contact may result in side effects.
     * This medication should not be used in the external ear canal of people
with perforated eardrums.
     * Do not use this product with an occlusive wrap unless your doctor
directs you to do so.  Systemic absorption of this drug is increased when
extensive areas of the body are treated, particularly if occlusive bandages
are used.  If it is necessary for you to use this drug under a wrap, follow
your doctor's instructions exactly, and do not leave the wrap in place longer
than specified.
     * If you are using this medication on a child's diaper area, do not put
tight-fitting diapers or plastic pants on the child.  This may lead to
increased systemic absorption of the drug and an increase in side effects.
     * Be sure to tell your doctor if you are pregnant.  If large amounts of
this drug are applied for prolonged periods, some of it will be absorbed and
may cross the placenta.  Although studies in humans have not been conducted,
birth defects have been observed in the offspring of animals that were given
large oral doses of this type of drug during pregnancy.  Also, tell your
doctor if you are breast-feeding an infant.  If absorbed through the skin,
small amounts of this medication pass into breast milk and may cause growth
suppression or a decrease in natural adrenocorticosteroid hormone production
in the nursing infant.

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The material contained here is "FOR INFORMATION ONLY" and should not replace 
the counsel and advice of your personal physician.  Promptly consulting your 
doctor is the best path to a quick and successful resolution of any medical 
problem.
