$Unique_ID{BRK01809}
$Pretitle{}
$Title{ACETAMINOPHEN AND CODEINE COMBINATION}
$Subject{acetaminophen with codeine (various manufacturers)
Aceta with Codeine (Century)
Capital with Codeine (Carnrick)
Phenaphen-650 with Codeine (Robins)
Phenaphen with Codeine (Robins)
Tylenol with Codeine (McNeil)
Ty-tabs (Major)}
$Volume{}
$Log{
Phenaphen with Codeine No. 3*0180901.scf
Tylenol No. 2*0180903.scf
Tylenol No. 3*0180904.scf
Tylenol No. 4*0180905.scf}

Copyright (C) 1991 Publications International, Ltd.


ACETAMINOPHEN AND CODEINE COMBINATION
------------------------------------------------------------------------------

BRAND NAMES (Manufacturers):
     acetaminophen with codeine (various manufacturers)
     Aceta with Codeine (Century)
     Capital with Codeine (Carnrick)
     Phenaphen-650 with Codeine (Robins)
     Phenaphen with Codeine (Robins)
     Tylenol with Codeine (McNeil)
     Ty-tabs (Major)
TYPE OF DRUG:
     Analgesic combination
INGREDIENTS:
     acetaminophen and codeine
DOSAGE FORMS:
     Tablets (300 mg acetaminophen with 7.5 mg, 15 mg, 30 mg, or 60 mg
       codeine; 325 mg acetaminophen with 30 mg or 60 mg codeine; 650 mg
       acetaminophen with 30 mg codeine)
     Capsules (325 mg acetaminophen with 15 mg, 30 mg, or 60 mg codeine)
     Oral elixir (120 mg acetaminophen and 12 mg codeine per 5-ml spoonful,
       with 7% alcohol)
     Note that on the label of the vial of tablets or capsules, the name of
       this drug is followed by a number.  This number refers to the amount of
       codeine present (#1 contains 7.5 mg codeine, #2 has 15 mg codeine, #3
       has 30 mg codeine, and #4 contains 60 mg codeine).
STORAGE:
     This medication should be stored at room temperature.  It should
       never be frozen.

USES

     Acetaminophen and codeine combination is used to relieve mild to severe
pain (formulations with higher codeine contents are used to relieve more
severe pain).  Codeine is a narcotic analgesic that acts on the central
nervous system (brain and spinal cord) to relieve pain.

TREATMENT

     In order to avoid stomach upset, you can take this medication with food
or milk.
     This medication works most effectively if you take it at the onset of
pain, rather than waiting until the pain becomes intense.
     Measure the dose of the liquid form of this medication carefully with a
specially designed 5-ml measuring spoon.  An ordinary kitchen teaspoon is not
accurate enough for measuring the dosage.
     If you are taking this medication on a regular schedule and you miss a
dose, take the missed dose as soon as possible, unless it is almost time for
the next dose.  In that case, don't take the missed dose at all; just return
to your regular dosing schedule.  Do not double the next dose.

SIDE EFFECTS

     Minor.

     Constipation, dizziness, drowsiness, dry mouth, false sense of
well-being, flushing, light-headedness, loss of appetite, nausea, painful or
difficult urination, or sweating.  These side effects should disappear as your
body adjusts to the medication.
     If you are constipated, increase the amount of fiber in your diet (fresh
fruits and vegetables, salads, bran, and whole-grain breads), exercise, and
drink more water (unless your doctor directs you to do otherwise).
     To reduce mouth dryness, chew sugarless gum or suck on ice chips or hard
candy.
     If you feel dizzy or light-headed, sit or lie down for a while; get up
slowly from a sitting or reclining position, and be careful on stairs.

     Major.

     Tell your doctor about any side effects that are persistent or
particularly bothersome.  IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about
anxiety, difficulty in breathing, excitation, fatigue, palpitations, rash,
restlessness, sore throat and fever, tremors, unusual bleeding or bruising,
weakness, or yellowing of the eyes or skin.

INTERACTIONS

     This medication interacts with several other types of drugs:
     1. Concurrent use with other central nervous system depressants (such as
alcohol, antihistamines, barbiturates, benzodiazepine tranquilizers, muscle
relaxants, and phenothiazine tranquilizers) or with tricyclic antidepressants
can cause extreme drowsiness.
     2. A monoamine oxidase (MAO) inhibitor taken within 14 days of this
medication can lead to unpredictable and severe side effects.
     3. Long-term use and high doses of the acetaminophen portion of this
medication can increase the effects of oral anticoagulants (blood thinners,
such as warfarin); this combination may lead to bleeding complications.
     4. Anticonvulsants (antiseizure medications), barbiturates, and alcohol
can increase the liver toxicity caused by large doses of the acetaminophen
portion of this medication.
     BE SURE TO TELL YOUR DOCTOR about any medications you are currently
taking, especially any listed above.

WARNINGS

     * Tell your doctor about unusual or allergic reactions you have had to
any medications, especially to acetaminophen, codeine, or other narcotic
analgesics (such as hydrocodone, hydromorphone, meperidine, methadone,
morphine, oxycodone, and propoxyphene).
     * Tell your doctor if you now have or if you have ever had an acute
abdominal condition, asthma, a blood disorder, brain disease, colitis,
epilepsy, gallstones or gallbladder disease, head injuries, heart disease,
kidney disease, liver disease, lung disease, mental illness, prostate disease,
thyroid disease, or urethral strictures.
     * If this drug makes you dizzy or drowsy, do not take part in any
activity that requires alertness, such as driving a car or operating
potentially dangerous equipment.
     * Before having surgery or any other medical or dental treatment, be sure
to tell your doctor or dentist that you are taking this medication.
     * Because this product contains codeine, it has the potential for abuse
and must be used with caution.  Usually, it should not be taken on a regular
schedule for longer than ten days at a time.  Tolerance develops quickly; do
not increase the dosage or stop taking the drug abruptly unless you first
consult your doctor.  If you have been taking large amounts of this medication
for long periods, you may experience a withdrawal reaction (diarrhea,
excessive yawning, gooseflesh, irritability, muscle aches, nausea, runny nose,
shivering, sleep disorders, stomach cramps, sweating, trembling, vomiting, or
weakness).  Your doctor may, therefore, want to reduce the dosage gradually.
     * Because this product contains acetaminophen, additional drugs that
contain acetaminophen should not be taken without your doctor's approval.  Be
sure to check the labels on over-the-counter pain, sinus, allergy, asthma,
diet, cough, and cold products before you use them in order to see if they
contain acetaminophen.
     * Be sure to tell your doctor if you are pregnant.  The effects of this
medication during pregnancy have not been thoroughly studied in humans.
Codeine used regularly in large doses during pregnancy can result in addiction
of the fetus, leading to withdrawal symptoms (diarrhea, excessive crying,
excessive yawning, irritability, fever, sneezing, tremors, or vomiting) at
birth.  Also, tell your doctor if you are breast-feeding an infant.  Small
amounts of this drug may pass into breast milk and cause drowsiness in the
nursing infant.

----------------

The material contained here is "FOR INFORMATION ONLY" and should not replace 
the counsel and advice of your personal physician.  Promptly consulting your 
doctor is the best path to a quick and successful resolution of any medical 
problem.
