$Unique_ID{BRK01366}
$Pretitle{Ill Defined Symptoms and Rare Diseases}
$Title{What is Hand-Schuller-Christian Disease?}
$Subject{Hand-Schuller-Christian biopsy}
$Volume{N-7}
$Log{}

Copyright (c) 1991   Tribune Media Services, Inc.


What is Hand-Schuller-Christian Disease?


------------------------------------------------------------------------------

QUESTION:  I have what I believe to be an unusual problem.  At least I have
never heard of it before and wonder if its familiar to you.  I get small lumps
usually in my arms that are quite sore.  My doctor feels I need a biopsy.  He
mentioned a disease he feels I may have (something-Christian?) Can you explain
this to me?  Do I need the biopsy?

------------------------------------------------------------------------------

ANSWER:  When "bumps" like yours become a problem, the only sure way of making
a diagnosis is to take a biopsy.  By taking a small sample of the lump, and
producing microscopic slides for examination, a pathologist can identify the
types of cells and narrow down the diagnosis to one or two possibilities.
"Hand-Schuller-Christian Disease (HSC)" is also known as "Histiocytosis X" for
the bumps in this disease turn out to be composed of masses of histiocytes.
These cells originate in the marrow, normally form a type of white blood cell,
but in this condition may be found growing in many organs including the lungs
and bone and is associated with lymphadenopathy (swollen glands) often felt as
bumps.  No cause has yet been discovered that explains this condition.
However this disease is more common in children and young adults, and is less
commonly seen in adults, and may not be the diagnosis in your case.  That is
why a biopsy in your situation is so essential, for a clear diagnosis is
needed upon which to base the treatment and therapy.  An interesting point to
note, patients with HSC Disease sometimes recover spontaneously, without any
treatment.
ÿ
----------------

The material contained here is "FOR INFORMATION ONLY" and should not replace 
the counsel and advice of your personal physician.  Promptly consulting your 
doctor is the best path to a quick and successful resolution of any medical 
problem.
