$Unique_ID{BRK01905}
$Pretitle{}
$Title{CODEINE AND IODINATED GLYCEROL COMBINATION}
$Subject{Iophen-C (various manufacturers)
Oridol C (LuChem)
Tussi-Organidin (Wallace)
Tussi-R-Gen (Goldline)}
$Volume{}
$Log{}

Copyright (C) 1991 Publications International, Ltd.


CODEINE AND IODINATED GLYCEROL COMBINATION
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BRAND NAMES (Manufacturers):
     Iophen-C (various manufacturers)
     Oridol C (LuChem)
     Tussi-Organidin (Wallace)
     Tussi-R-Gen (Goldline)
TYPE OF DRUG:
     Cough suppressant and expectorant combination
INGREDIENTS:
     codeine and iodinated glycerol
DOSAGE FORM:
     Oral liquid (10 mg codeine and 30 mg iodinated glycerol per 5-ml
       spoonful)
STORAGE:
     Codeine and iodinated glycerol combination should be stored at room
       temperature in a tightly closed container.  Avoid exposure of this
       medication to high temperatures.

USES

     This drug is used to relieve coughs due to colds or infection or
inflammation of the upper respiratory tract.  Iodinated glycerol is an
expectorant, which loosens bronchial secretions.  Codeine is a narcotic cough
suppressant, which acts on the cough center in the brain.

TREATMENT

     You can take codeine and iodinated glycerol combination on an empty
stomach or, to avoid stomach irritation, with food or milk (as directed by
your doctor).
     Each dose should be measured carefully with a specially designed 5-ml
measuring spoon.  An ordinary kitchen teaspoon is not accurate enough.
     To help loosen the mucus in the bronchi, you should drink a glass of
water after each dose.
     If you miss a dose of this medication, take the missed one as soon as
possible, unless it is almost time for the next dose.  In that case, do not
take the missed dose at all; just return to your regular dosing schedule.  Do
not double the next dose.

SIDE EFFECTS

     Minor.

Constipation, dizziness, drowsiness, nausea, restlessness, stomach upset,
vomiting, or weakness.  These side effects should disappear as your body
adjusts to the medication.
     If you feel dizzy, sit or lie down for a while; get up slowly from a
sitting or reclining position, and be careful on stairs.
     To relieve constipation, increase the amount of fiber in your
diet (fresh fruits and vegetables, salads, bran, and whole-grain
breads), exercise, and drink more water (unless your doctor
directs you to do otherwise).

     Major.

     Tell your doctor about any side effects that are persistent or
particularly bothersome.  IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about
blurred vision; cold, clammy skin; confusion; difficulty in breathing;
fainting; skin rash; or swollen lymph nodes.

INTERACTIONS

This drug can interact with other types of drugs:
     1. Concurrent use with other central nervous system depressants (such as
alcohol, barbiturates, benzodiazepine tranquilizers, muscle relaxants, other
narcotics, pain medications, phenothiazine tranquilizers, and sleeping
medications) or with tricyclic antidepressants can lead to extreme drowsiness.
     2. Use of a monoamine oxidase (MAO) inhibitor within 14 days of use of
codeine and iodinated glycerol combination can lead to serious side effects.
     3. The iodine component of iodinated glycerol can increase the side
effects of lithium on the thyroid gland.  It can also increase the effects of
antithyroid medications.
     4. Cimetidine combined with this medication can cause confusion,
disorientation, and shortness of breath.
     Before starting codeine and iodinated glycerol combination, BE SURE TO
TELL YOUR DOCTOR about any medications you are currently taking, especially
any of those listed above.

WARNINGS

     * Tell your doctor about unusual or allergic reactions you have had to
any medications, especially to codeine, or to other narcotics (such as
hydrocodone, hydromorphone, meperidine, methadone, opium, oxycodone,
propoxyphene, and pentazocine), or to iodinated glycerol, iodine, or
iodine-containing dyes.
     * Before starting to take this medication, be sure to tell your doctor if
you now have or if you have ever had acne, asthma, brain disease, cystic
fibrosis, gallstones or gallbladder disease, gastrointestinal diseases, heart
disease, kidney disease, liver disease, lung disease, mental disorders,
enlarged prostate gland, or thyroid disease.
     * If this drug makes you dizzy or drowsy, do not take part in activities
that require alertness, such as driving a car or operating potentially
dangerous equipment.
     * While you are taking this medication, drink at least eight glasses of
water a day (to help loosen bronchial secretions).
     * Because this product contains codeine, it has the potential for abuse
and must be used with caution.  Tolerance may develop quickly; you should not
use it in higher doses, or for longer periods, than recommended by your
doctor.  If you have been taking it for longer than several weeks, do not stop
taking it until you first check with your doctor.  Stopping the drug abruptly
can lead to a withdrawal reaction (body aches, diarrhea, gooseflesh, vomiting,
restlessness, runny nose, sneezing, sweating, trembling, or excessive
yawning).  Your doctor may, therefore, want to reduce your dosage gradually.
     * Be sure to tell your doctor if you are pregnant.  This medication
should not be taken during pregnancy.  Large amounts of codeine taken during
pregnancy can lead to addiction in the developing fetus, resulting in
withdrawal reactions in the newborn infant.  Iodinated glycerol can cause
goiter (an enlarged thyroid gland) in the developing fetus.  Also, tell your
doctor if you are breast-feeding an infant.  Both codeine and iodinated
glycerol can pass into the breast milk and cause side effects in the nursing
infant.

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The material contained here is "FOR INFORMATION ONLY" and should not replace 
the counsel and advice of your personal physician.  Promptly consulting your 
doctor is the best path to a quick and successful resolution of any medical 
problem.
