$Unique_ID{BRK01988}
$Pretitle{}
$Title{IBUPROFEN}
$Subject{Aches-N-Pain (Lederle)
Advil (Whitehall)
Genpril (Goldline)
Haltran (Upjohn)
Ibuprin (Thompson Medical)
ibuprofen (various manufacturers)
Ifen (Everett)
Medipren (McNeil)
Midol 200 (Glenbrook)
Motrin (Upjohn)
Motrin IB
Nuprin (Bristol-Myers)
Pamprin-IB (Chettem)
Rufen (Boots)
Trendar (Whitehall)}
$Volume{}
$Log{
Motrin 300*0198801.scf
Motrin 400*0198802.scf
Motrin 600*0198803.scf
Rufen 400*0198804.scf
Rufen 600*0198805.scf}

Copyright (C) 1991 Publications International, Ltd.


IBUPROFEN
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BRAND NAMES (Manufacturers):
     Aches-N-Pain [*] (Lederle)
     Advil [*] (Whitehall)
     Genpril [*] (Goldline)
     Haltran [*] (Upjohn)
     Ibuprin [*] (Thompson Medical)
     ibuprofen (various manufacturers)
     Ifen (Everett)
     Medipren [*] (McNeil)
     Midol 200 [*] (Glenbrook)
     Motrin (Upjohn)
     Motrin IB [*]
     Nuprin [*] (Bristol-Myers)
     Pamprin-IB [*] (Chettem)
     Rufen (Boots)
     Trendar [*] (Whitehall)
  *  Available over-the-counter (without a prescription) as 200-mg tablets.
TYPE OF DRUG:
     Nonsteroidal anti-inflammatory analgesic
INGREDIENT:
     ibuprofen
DOSAGE FORM:
     Tablets (200 mg, 300 mg, 400 mg, 600 mg, and 800 mg)
STORAGE:
     Store in a tightly closed container at room temperature away from heat
and direct sunlight.

USES

     Ibuprofen is used to treat the inflammation (pain, swelling, stiffness)
of certain types of arthritis, gout, bursitis, and tendinitis.  It is also
used to treat painful menstruation.  Ibuprofen has been shown to block
production of certain body chemicals, called prostaglandins, that may trigger
pain.  However, it is not yet fully understood how it does so.

TREATMENT

     You should take this medication on an empty stomach 30 to 60 minutes
before meals or two hours after meals, so that it gets into your bloodstream
quickly.  However, to decrease stomach irritation, your doctor may want you to
take the medication with food or antacids.
     If you are taking ibuprofen to relieve arthritis, you must take it
regularly as directed by your doctor.  It may take up to two weeks before you
feel the full effects of this medication.  Ibuprofen does not cure arthritis,
but it will help to control the condition as long as you continue to take it.
     It is important to take ibuprofen on schedule and not to miss any doses.
If you do miss a dose, take it as soon as possible, unless it is almost time
for your next dose.  In that case, don't take the missed dose at all; just
return to your regular dosing schedule.  Do not double the next dose.

SIDE EFFECTS

     Minor.

     Bloating, constipation, diarrhea, difficulty in sleeping, dizziness,
drowsiness, headache, heartburn, indigestion, light-headedness, loss of
appetite, nausea, nervousness, soreness of the mouth, unusual sweating, or
vomiting.  As your body adjusts to the drug, these side effects should
disappear.
     To relieve constipation, increase the amount of fiber in your diet (fresh
fruits and vegetables, salads, bran, and whole-grain breads), exercise, and
drink more water (unless your doctor directs you to do otherwise).
     If you become dizzy or light-headed, sit or lie down for a while; get up
slowly from a sitting or reclining position, and be careful on stairs.

     Major.

     If any side effects are persistent or particularly bothersome, you should
report them to your doctor.  IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR
about bloody or black, tarry stools; blurred vision; confusion; depression;
difficult or painful urination; palpitations; a problem with hearing; ringing
or buzzing in your ears; skin rash, hives, or itching; stomach pain; swelling
of the feet; tightness in the chest; unexplained sore throat and fever;
unusual bleeding or bruising; unusual fatigue or weakness; unusual weight
gain; wheezing or difficulty in breathing; or yellowing of the eyes or skin.

INTERACTIONS

     Ibuprofen interacts with several other types of medications:
     1. Anticoagulants (blood thinners, such as warfarin) can lead to an
increase in bleeding complications.
     2. Aspirin, other salicylates, and other anti-inflammatory medications
can increase stomach irritation.  Aspirin may also decrease the effectiveness
of ibuprofen; therefore, it should not be used concurrently with ibuprofen.
     3. Ibuprofen can interact with diuretics (water pills).
     4. Probenecid may increase blood levels of ibuprofen, which may increase
the risk of side effects.
     5. The action of beta blockers may be decreased by this drug.
     BE SURE TO TELL YOUR DOCTOR about any medications you are currently
taking, especially any listed above.

WARNINGS

     * Before you start to take this medication, it is important to tell your
doctor if you have ever had unusual or allergic reactions to ibuprofen, or to
any of the other chemically related drugs (aspirin, other salicylates,
diclofenac, diflunisal, fenoprofen, flurbiprofen, indomethacin, ketoprofen,
meclofenamate, mefenamic acid, naproxen, oxyphenbutazone, phenylbutazone,
piroxicam, sulindac, or tolmetin).
     * Tell your doctor if you now have or if you have ever had bleeding
problems, colitis, stomach ulcers or other stomach problems, epilepsy, heart
disease, high blood pressure, asthma, kidney disease, liver disease, mental
illness, or Parkinson's disease.
     * If ibuprofen makes you dizzy or drowsy, do not take part in any
activity that requires alertness, such as driving a car or operating
potentially dangerous machinery.
     * Because this drug can prolong bleeding time, tell your doctor or
dentist you are taking this drug before having surgery or other medical or
dental treatment.
     * Stomach problems are more likely to occur if you take aspirin regularly
or drink alcohol while being treated with this medication.  These should,
therefore, be avoided (unless your doctor directs you to do otherwise).
     * The elderly may be at increased risk for experiencing side effects of
this drug.
     * Be sure to tell your doctor if you are pregnant.  This type of
medication can cause unwanted effects to the heart or blood flow of the fetus.
Studies in animals have also shown that this type of medicine, if taken late
in pregnancy, may increase the length of pregnancy, prolong labor, or cause
other problems during delivery.  Also, tell your doctor if you are
breast-feeding an infant.  Small amounts of ibuprofen can pass into breast
milk.

----------------

The material contained here is "FOR INFORMATION ONLY" and should not replace 
the counsel and advice of your personal physician.  Promptly consulting your 
doctor is the best path to a quick and successful resolution of any medical 
problem.
