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$Title{CINOXACIN}
$Subject{Cinobac (Dista)}
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Copyright (C) 1991 Publications International, Ltd.


CINOXACIN
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BRAND NAME (Manufacturer):
     Cinobac (Dista)
TYPE OF DRUG:
     Antibiotic
INGREDIENT:
     cinoxacin
DOSAGE FORM:
     Capsules (250 mg and 500 mg)
STORAGE:
     Cinoxacin capsules should be stored at room temperature in a tightly
       closed container.

USES

     Cinoxacin is an antibiotic that is used to treat bacterial urinary tract
infections.  It chemically attaches to the bacteria, preventing their growth
and multiplication.  It kills susceptible bacteria, but it is not effective
against viruses, parasites, or fungi.

TREATMENT

     In order to prevent stomach irritation, you can take cinoxacin with food
or with a full glass of water or milk (unless your doctor directs you to do
otherwise).
     Cinoxacin works best when the level of medicine in your urine is kept
constant.  It is best, therefore, to take the doses at evenly spaced intervals
day and night.  For example, if you are to take four doses a day, the doses
should be spaced six hours apart.
     Try not to miss any doses of this medication.  If you do miss a dose,
take it as soon as you remember.  However, if you do not remember to take the
missed dose until it is almost time for your next dose, take the missed dose
immediately; space the following dose about halfway through the regular
interval between doses; then continue with your regular dosing schedule.
     It is important to continue to take this medication for the entire time
prescribed by your doctor (usually seven to 14 days), even if the symptoms
disappear before the end of that period.  If you stop taking the drug too
soon, resistant bacteria are given a chance to continue growing, and your
infection could recur.

SIDE EFFECTS

     Minor.

     Abdominal cramps, diarrhea, dizziness, headache, increased sensitivity of
the eyes to light, insomnia, loss of appetite, nausea, nervousness, or rectal
itching.  These side effects should disappear as your body adjusts to the
medication.
     To relieve the increased sensitivity of your eyes to light, avoid
prolonged exposure to sunlight and bright lights, and wear sunglasses.

     Major.

     Tell your doctor about any side effects that are persistent or
particularly bothersome.  IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about
confusion, itching, rapid weight gain (three to five pounds within a week),
ringing in the ears, skin rash, tingling sensations, visual disturbances, or
yellowing of the eyes or skin.  Also, if the symptoms of your infection do not
improve within several days, contact your doctor.

INTERACTIONS

     Probenecid blocks the excretion of cinoxacin into the urinary tract,
decreasing its effectiveness.
     BE SURE TO TELL YOUR DOCTOR about any medications you are currently
taking, especially probenecid.

WARNINGS

     * Tell your doctor about unusual or allergic reactions you have had to
any medications, especially to cinoxacin, nalidixic acid, or norfloxacin.
     * Tell your doctor if you now have or if you have ever had kidney disease
or liver disease.
     * If this drug makes you dizzy, do not take part in any activity that
requires alertness, such as driving a car or operating potentially dangerous
equipment.
     *  Cinoxacin has been prescribed for your current infection only.
Another infection later on, or one that someone else has, may require a
different medicine.  Do not give your medicine to other people or use it for
another infection unless your doctor specifically directs you to do so.
     *  Be sure to tell your doctor if you are pregnant.  Although cinoxacin
use appears to be safe during pregnancy, extensive studies in humans have not
been conducted.  Also, tell your doctor if you are breast-feeding an infant.
It is not known whether cinoxacin passes into breast milk.

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The material contained here is "FOR INFORMATION ONLY" and should not replace 
the counsel and advice of your personal physician.  Promptly consulting your 
doctor is the best path to a quick and successful resolution of any medical 
problem.
